Hollywood superstar Ben Stiller and his wife of 17 years, Christine Taylor, are calling time on their marriage.

The pair exclusively announced their split in a joint statement to ET on Friday.

“With tremendous love and respect for each other, and the 18 years we spent together as a couple, we have made the decision to separate,” Stiller and Taylor said.

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“Our priority will continue to be raising our children as devoted parents and the closest of friends. We kindly ask that the media respect our privacy at this time.”

The couple, who met while filming a never-broadcast TV pilot called Heat Vision and Jack, tied the knot in May 2000 at an oceanfront ceremony in Kauai, Hawaii. “When I met her, I pretty much thought, ‘That’s the person,'” Stiller told ET in a 2007 interview. “It was like, ‘Wow, this is a great person. I love her.'”

The two welcomed daughter Ella Olivia in April 2002 and son Quinlin Dempsey in July 2005.

Throughout their marriage, Stiller, 51, and Taylor, 45, continued to share the screen — in projects like Zoolander, Dodgeball: A True Underdog Story, Tropic Thunder, Arrested Development and most recently, Zoolander 2.